WHAT IS DAXXIFY?
Daxxify is the newest FDA-approved neuromodulator used to smooth frown lines and other dynamic facial wrinkles. Like Botox, Jeuveau, and Dysport, it’s made from botulinum toxin type A. What sets Daxxify apart is its unique formulation that allows it to last longer — typically from 4-6 months for many patients.
Approved by the FDA in 2022, Daxxify (daxxibotulinumtoxinA-lanm) is the first injectable wrinkle relaxer to use a novel peptide stabilization system instead of human or animal-based ingredients. This innovation helps extend the duration of results, making Daxxify an appealing option for patients who want fewer treatments per year. While Daxxify may cost more per treatment, many patients find it balances out over time because it lasts longer and requires fewer appointments.
WHAT ARE THE BENEFITS OF DAXXIFY?
Daxxify is especially popular among patients looking for long-lasting results with fewer appointments.
- Softens moderate to severe frown lines and dynamic wrinkles
- Results typically lasting from 4-6 months
- Reduces the need for frequent retreatments — often only twice per year
- Smooths expression lines while preserving natural movement
- Short, well-tolerated treatment with no downtime
- Vegan formulation — no human or animal byproducts
WHICH AREAS CAN DAXXIFY BE ADMINISTERED?
Daxxify is FDA-approved for glabellar lines (frown lines between the eyebrows) but is often used off-label in other common treatment areas.
- Frown lines (glabellar lines between the brows)
- Forehead lines
- Crow’s feet around the eyes
- Bunny lines (sides of the nose)
- Eyebrow lift
- Vertical lip lines (smoker’s lines)
- Chin dimpling or pebbled texture
- Downturned mouth corners
- Platysmal bands in the neck
HOW IS DAXXIFY ADMINISTERED?
Daxxify is injected into specific facial muscles using a very fine needle. We begin by assessing your facial anatomy and movement patterns to create a personalized treatment plan. Most sessions take about 15 to 30 minutes from start to finish.
The number of injection points and units will depend on the area being treated and the strength of your facial muscles. Daxxify is well-tolerated and doesn’t require any numbing, although we can use ice or topical anesthetic if desired.
HOW LONG DOES DAXXIFY LAST?
Daxxify is known for its extended duration. In clinical studies, most patients saw results that lasted between 4 and 6 months, with a small percentage seeing effects beyond that.
Because it lasts longer than traditional neurotoxins, you may only need 2-3 treatments per year to maintain results. This is ideal for patients who prefer a lower-maintenance approach or want to avoid frequent appointments.
Over time, consistent treatment can help retrain your facial muscles to rest in a more relaxed state, making results even more effective and longer-lasting.
WHEN WILL I SEE THE RESULTS FROM DAXXIFY?
Initial results typically appear within 2 to 4 days after treatment, with full results developing by day 10 to 14. Wrinkles will gradually soften, giving your face a smoother, more rested look.
Daxxify provides natural-looking results — your expressions remain intact, but without harsh creasing.
WHAT PREPARATION IS NEEDED FOR DAXXIFY?
The preparation for Daxxify is similar to other neurotoxins. To minimize bruising or swelling:
- Avoid aspirin, ibuprofen, and other blood thinners for 7 to 10 days before treatment
- Pause supplements like fish oil, vitamin E, turmeric, or St. John’s Wort
- Limit alcohol for at least 24 hours prior
- Let us know if you have a history of cold sores or are on prescription medications
Always consult with your provider before making changes to prescribed medications.
WHAT CAN I ANTICIPATE AFTER TREATMENT?
Most patients return to their normal day immediately following treatment. You may notice mild redness, small bumps, or slight tenderness at the injection sites for a few hours. Bruising is possible but not common.
For best results:
- Avoid vigorous exercise for 4 to 6 hours
- Don’t rub or massage treated areas
- Stay upright for 4 hours following treatment
If needed, Tylenol can be used to relieve any minor soreness. Makeup can usually be applied after 15 to 30 minutes.
DOES DAXXIFY HURT?
Daxxify injections are generally quick and cause minimal discomfort. Most patients describe the sensation as a small pinch. Numbing is usually not needed, but we can apply ice or topical numbing cream for added comfort if preferred.
Any post-treatment discomfort is mild and fades within a few hours.
IS DAXXIFY SAFE?
Yes, Daxxify is FDA-approved and has undergone extensive clinical testing. In trials involving thousands of patients, it was shown to be safe and well-tolerated.
Like all injectables, side effects may include redness, swelling, bruising, or tenderness at the injection site. Rarely, temporary eyelid drooping (ptosis) can occur. Choosing an experienced provider helps minimize risks and ensures proper technique.
DAXXIFY CONTRAINDICATIONS
Daxxify is not recommended for certain individuals. You should avoid Daxxify if you:
- Are pregnant or breastfeeding
- Have a known allergy to botulinum toxin
- Have a neuromuscular disorder like ALS or myasthenia gravis
- Have an active infection or inflammation at the injection site
If you’re unsure whether Daxxify is right for you, we’ll review your medical history and help you make an informed decision.
Your Next Step
Daxxify provides long-lasting wrinkle relaxation so you can enjoy your results for months longer between treatments. Schedule your Daxxify session today and see how extended smoothness can fit your lifestyle.