PDGF in Denver

PDGF+ (Platelet-Derived Growth Factor) is a regenerative skincare treatment that uses lab-engineered growth factors to support collagen production, tissue repair, and overall skin rejuvenation.
PDGF+ revitalizes your skin from the inside out – activating collagen, improving elasticity, and restoring hydration. It’s designed to strengthen thinning or crepey skin, smooth fine lines, and enhance tone and texture over time. PDGF+ can be used for the under-eyes, face, neck, chest, and scalp, and delivers natural-looking rejuvenation with minimal downtime.
This treatment is applied topically during microneedling treatments to enhance absorption and regenerative benefits – it is not an injectable treatment.
Ready to restore your skin from the inside out? Book an appointment at Injector 5280 and experience the next generation of regenerative aesthetics.
Benefits of Ariessence Pure PDGF+
PDGF+ activates fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid. Over time, this leads to measurable improvements in skin quality, density, and hydration. Patients turn to topical PDGF+ when they want visible rejuvenation without relying on filler volume or surgical intervention.
- Stimulates collagen, elastin, and hyaluronic acid production to improve skin structure and long-term firmness.
- Strengthens thinning and crepey skin by restoring density and resilience in delicate areas.
- Softens under-eye hollowness and discoloration for a brighter, more refreshed appearance.
- Boosts circulation and skin luminosity to enhance glow and even out tone.
- Speeds up post-treatment recovery when paired with microneedling, lasers, or other procedures.
- Delivers consistent, predictable results without relying on your hydration, stress, or blood quality.

Why Choose PDGF+ at Injector 5280?
- Skilled, credentialed practitioners delivering treatments in a boutique 5‑star med spa
- Pharmaceutical‑grade PDGF+ for consistent, predictable results every time
- Regenerates skin quality from within — strengthens, smooths, and revitalizes without adding filler volume
- Effective for multiple areas including face, under‑eyes, neck, chest, and scalp
- Convenient Denver location in Sunnyside with free private parking
- Top‑rated by local patients with easy online booking
Your Next Step
Rebuild your skin from the inside out with PDGF+ at Injector 5280. This advanced treatment stimulates collagen, elastin, and hydration to strengthen and rejuvenate your skin naturally — with minimal downtime and lasting benefits. Our team makes it simple, comfortable, and customized to you.
What Areas and Skin Concerns Can I Treat?
Ariessence Pure PDGF+ is ideal for precision rejuvenation in sensitive or hard-to-treat areas. It allows targeted placement directly where regeneration is needed most.
- Under-Eyes: Improves skin density and tone while reducing hollowness and fine lines.
- Perioral Area: Softens lines around the mouth and reinforces thinning skin without adding volume.
- Jawline and Cheeks: Supports skin firmness and elasticity when paired with other modalities.
- Scalp: Stimulates blood flow and supports hair growth when treated at the follicular level.
- Neck and Décolletage: Restores resilience and thickness in areas prone to laxity and sun damage.

How Long Do Results Last?
Most patients begin with a series of 3 PDGF+ sessions spaced 6–8 weeks apart. Collagen continues to build for months after each treatment. Once the initial foundation is complete, maintenance treatments 1–2 times per year help sustain results.
Longevity depends on your baseline skin quality and treatment area, but most clients enjoy visibly firmer, healthier skin for 6–12 months after their initial series.
When Will I See Results?
Improvements in hydration and skin texture may appear within the first few weeks. More significant changes — including improved tone, firmness, and under-eye smoothness — typically develop between weeks 4 and 8 as collagen production increases.
Because PDGF+ rebuilds skin over time, results are subtle, natural, and cumulative.
Why Ariessence Pure PDGF+ Outperforms PRP and Other Regenerative Therapies
- Pharmaceutical-Grade Potency: 100,000 to 300,000x stronger than PRP
- Stable & Consistent: No reliance on your own hydration, stress, or lifestyle factors
- Sterile Formula: Only 4 ingredients — water, sodium acetate, hyaluronic acid, and synthetic PDGF dimer (sh-polypeptide-59)
- Proven Safety: 4 FDA-approved indications and over 5 million treatments performed worldwide
- Under-Eye Rejuvenation: Unlike filler, which may migrate or look puffy under the eyes, PDGF+ strengthens the skin from within for a smooth, natural result
How to Prepare for PDGF+ Treatment
- Two Weeks Before: Avoid dental work, vaccines, or other elective procedures close to your appointment.
- 48 Hours Before: Avoid alcohol, aspirin, and NSAIDs to minimize bruising. Consider starting Arnica.
- Day of Treatment: Eat a light meal beforehand. Arrive with clean skin; we will prep the area prior to treatment.
What to Expect After Treatment
You may notice mild redness, swelling, or pinpoint bruising immediately after treatment — especially in sensitive areas like the under-eyes. These effects usually resolve within 24–48 hours. Results develop gradually, with minimal downtime and no risk of filler overcorrection or migration.
Pricing for PDGF+
Cost: $800 per syringe
Most patients require one syringe for under-eye treatment. Full scalp or larger areas may require two syringes. A treatment plan will be discussed during your consultation.

Is It Painful?
Discomfort is minimal. The treatment may feel like a quick pinch or gentle pressure. Topical numbing is available upon request and often used when treating under the eyes or scalp. Any post-treatment tenderness fades within hours.
Is PDGF+ Safe?
Yes. Ariessence Pure PDGF+ is a sterile, lab-engineered treatment with a clean ingredient list and no human-derived components. It has been used safely in dermatology, ophthalmology, and orthopedic medicine — and is well tolerated in aesthetic applications with virtually no systemic side effects.
Ariessence Pure PDGF+ Contraindications
PDGF+ is safe for most healthy adults, but you may not be a candidate if you:
- Are pregnant or breastfeeding
- Have active infection or open wounds in the treatment area
- Recently took Accutane (within 6 months)
- Received immunosuppressive treatment in the past 24 hours
- Have a poorly controlled autoimmune condition
We’ll review your full health history before beginning any procedure.
Patient Testimonials





What I appreciate most about Meaghan is how much she listens. I’ll tell her what I’m seeing, what’s bothering me, or what I think I want, and she’ll tell me what we should do, what we shouldn’t do, and when we need to leave something alone. She never pushes treatments or makes me feel like I need more.
She has transformed my face in the best possible way while still making me look like ME. Refreshed, balanced, natural, and never overdone. I trust her completely with my face, and there is no one else I would go to. She is truly incredible at what she does.




A special thank you to Megan—she is amazing! Her work is so precise, and she takes the time to make sure everything looks natural and beautiful. She also follows up after every appointment to check on your healing, provides clear aftercare instructions, and genuinely cares about every little detail. You can tell she truly wants the best results for her clients.
I honestly don’t see myself going anywhere else. Injector 5280 has earned my trust, and I’ll definitely be coming back for all my future treatments. Highly recommend!



She took the time to explain everything thoroughly, answered all of my questions, and made sure I felt confident with my treatment plan. You can tell she truly cares about her patients and takes so much pride in her work.
I know Sculptra is a treatment that builds beautiful results over time, so I’m already so excited to watch my collagen develop. I genuinely can’t wait to go back for my next appointment! If you’re looking for someone who is knowledgeable, talented, honest, and makes the experience feel effortless, Shannon is the one. Five stars isn’t enough!






She is a genius! After years of getting Botox and Dysport elsewhere, switching to her at Injector 5280 was the best decision I’ve made for my skin.
Megan listens intently and dials your treatment plan in immediately. She understands facial anatomy perfectly and mastered my protocol in just two appointments. We just did under-eye Jelly Roll Botox to fix my lower lid crinkling. She was wonderfully transparent about the potential for temporary puffiness, but by day six, it already looks smoother and I have experienced no puffiness at all.
She’s phenomenal at looking at overall facial symmetry, and adapting the injection placement and the amounts to help with small problem areas like jowls, platysmal bands, etc.
I have also done Sculptra and chin shadowing filler with Megan. She’s just as precise and talented with fillers as she is with Botox and Dysport. It looks absolutely amazing. She really gives you a holistic & subtle facial overhaul.
Megan is in a league of her own-I can’t recommend her more highly!
Also worth mentioning -The med spa itself is absolutely gorgeous, and the staff is all amazing and they have plenty of parking:)










After doing a lot of research, I found Megan Welsh. I went to her a few times (Botox and lip filler) and she did an incredible job - so much so that the plastic surgeon she worked for at the time put my before and after lips (courtesy of Megan) on 5’ tall printout in the office.
Then, Megan moved to Denver and I thought I’d have to give up my new favorite treatment.
But life happened, and career brought me to Denver. I have been going to see Megan again now that we are in the same city and am so happy I didn’t trust my lips to anyone else. She has an eye for perfection, and will share her honest, professional opinion if she thinks that something I am asking for may not look ideal.
Don’t keep looking - you have definitely found the right person if you book with Megan and are trying to accomplish a fuller but extremely natural look.


Nicole is truly the best aesthetician I’ve ever been to — she’s so knowledgeable, gentle, and makes every treatment feel personalized and relaxing. My skin has never looked better thanks to her care and attention to detail.
Sari is equally incredible as my injector. She has such an eye for natural results and really listens to what I want. I always leave feeling confident, refreshed, and never overdone.


The facility is very cozy, welcoming and clean!! Everyone is nice, accommodating and I felt valued as a customer!



Edit: came back here to get lip filler with Sari and she was so knowledgeable and skilled. My lips look incredible and she was super honest about what my lips could handle. I would highly recommend 🙂 the entire staff is super sweet
Plus, Kellie and April do amazing procedures while obtaining amazing results! You can't go wrong here! Thanks to Injector 5280

I had several rounds of treatments (CoolSculpting Elite and EmSculpt). Kellie always explains everything and makes sure I am comfortable. I love that she tells me what she's doing and her thought process, because I am a details gal. Her whole demeanor is excited, supportive, and uplifting. I love chatting with her. She also has amazing TV recommendations which is a plus as some of the procedures are long.
Results take 2-4 months and I just passed one month and am so pleased with my results already. I can't recommend Injector 5280 enough.
⭐️⭐️⭐️⭐️⭐️
April and Kellie have excellent experience in the many treatments they provide, and are able
to distill and convey their knowledge in a personable and effective manner. This puts anyone at ease, and helps one comfortably and confidently choose the right treatment for themselves.
They are also upfront and honest about what to expect and when to expect results both of which help set accurate expectations and builds trust - which was something the other clinics overlooked.
So, if you are interested but unsure about what treatment, procedure or even clinic is right for you, I wholeheartedly recommend the Injector 5280 clinic and team!
I eventually decided to do the treatment, and Kellie took excellent care of me! She was in touch with me throughout the process, checking in on my results and available to answer any questions I might have. I felt comfortable and safe throughout the treatment, and I am very satisfied with my results! I highly recommend Injector 5280!




Lauren was extremely knowledgeable, friendly, funny, and professional. We had a wonderful experience and we will absolutely be back! Great atmosphere. Who knew you could actually have fun while having needles poked into your face!








You can have that boost you need to feel better about yourself and be kinder to yourself. Your personal goals no longer seem insurmountable. And these ladies are so kind and honest. They coach you through finding what is right for you and your body. I cannot recommend them enough!



As for their service: they offer the talent and customer service that you would hope for and that most places only dream about being able to provide. They're down to earth. Whenever I've had any issues or concerns they make sure we are on the same page before moving forward. Their friendliness and service comes from the heart. They are both talented artists.
The final thought: they are dependable, creative, loving, and valuable.


Comparison: PDGF+ vs PRP vs Dermal Fillers
| Treatment | What It Is | Strengths | Limitations | Best For |
|---|---|---|---|---|
| Ariessence Pure PDGF+ | Pharmaceutical-grade Platelet-Derived Growth Factor, lab-engineered for skin and tissue regeneration. |
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| PRP | Platelet-Rich Plasma derived from your own blood, spun in a centrifuge to concentrate growth factors. |
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| Dermal Fillers | Injectable gels (often hyaluronic acid) that restore volume and shape instantly. |
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